What type of therapy includes aromatase inhibitors and antiestrogens?

Hormonal therapy is the correct choice as it specifically involves the use of medications, such as aromatase inhibitors and antiestrogens, to target hormone-sensitive cancers, most commonly breast cancer. Aromatase inhibitors work by blocking the conversion of androgens to estrogens, thereby reducing estrogen levels in the body, which can help slow or stop the growth of hormone-receptor-positive tumors. Antiestrogens, on the other hand, work by blocking the effects of estrogen on tumors. This type of therapy is designed to exploit the dependency of certain tumors on hormones for growth, making it a critical component of treatment for patients with cancer that has hormone receptors.

Other types of therapies, such as chemotherapy, immunotherapy, and radiotherapy, employ different mechanisms to combat cancer. Chemotherapy uses drugs to kill or slow the growth of rapidly dividing cancer cells, immunotherapy harnesses the body's immune system to fight cancer, and radiotherapy utilizes high doses of radiation to kill cancer cells or shrink tumors. These modalities do not specifically involve the hormonal manipulation that is characteristic of hormonal therapy, which is focused on treating hormone-sensitive malignancies.