What does the CA-125 marker help evaluate in ovarian cancer patients?

The CA-125 marker plays a significant role in the management of ovarian cancer patients by serving multiple functions, which is why the most comprehensive answer encompasses all these aspects.

First, CA-125 is often utilized in the diagnostic process for ovarian cancer. Elevated levels of this marker can be indicative of the presence of ovarian cancer, especially in women with appropriate clinical symptoms. It is, however, not solely used for diagnosis, as elevated CA-125 levels can occur in other conditions.

Secondly, CA-125 is invaluable in monitoring treatment response. After the initiation of treatment, measuring CA-125 levels can help clinicians determine how well the therapy is working. A decrease in CA-125 levels typically suggests that the treatment is effective, while persistent high levels may indicate that the disease is not responding.

Lastly, CA-125 is also useful in monitoring for disease recurrence. Following treatment, regular assessment of CA-125 levels can help detect a resurgence of ovarian cancer at an early stage. An increase in CA-125 may prompt further imaging studies or other evaluations to assess for the potential return of the disease.

Thus, CA-125 marker is instrumental in diagnosing, assessing treatment response, and detecting recurrence of ovarian cancer, making the choice that includes all these functions