Neoadjuvant therapy is administered at what point in relation to surgery?

Neoadjuvant therapy is specifically given before surgery with the aim of reducing the size of the tumor or eliminating metastatic disease, which can make surgical removal more successful or less extensive. This approach can also help assess how well the tumor responds to treatment, providing valuable information about its biology and behavior. Administering this therapy before surgery can sometimes lead to better surgical outcomes and ultimately improve the prognosis for patients. It's a strategic way to potentially shrink the tumor and make it operable, or to allow for a less invasive surgical approach.